Manoj, Meredith, and Braden’s collaborative work with Daniel Gentile from Kevan Shokat’s laboratory on the identification and characterisation of novel Ras inhibitors published in Cell Chemical Biology.
Braden, Manoj and Meredith’s paper on the activation of class IA PI3Ks by membrane localised HRas published in JBC. Coincides with Braden being accepted into medical school at the same time. Congrats all around.
Manoj Rathinaswarmy joins the lab as graduate student.
The collaborative project examining malarial inhibitors from Dr Stuart Schreiber’s laboratory was just published in Nature. Congratulations to Jacob and Gillian. The work was also written up in BBC news!
John just returned from giving a talk at the Phospholipase A2 meeting in La Jolla honouring his previous supervisor Ed Dennis. Photo attached of all of the former Dennis lab trainees over the years.
Melissa and Jacob’s paper in J Med Chem has been accepted. This collaboration with the Shokat lab at UCSF discusses our use of structure guided drug design to make new PI4KB inhibitors.
First last author paper from the group published in Protein Science. Also first paper published with the new mass spectrometer. Congratulations to Melissa, Jacob, and Meredith.
PTEN HDX-MS paper published today in Biochemical Journal from John’s postdoc. Congratulations to Glenn.
The new mass spectrometer has arrived, time to get some H/D exchange experiments running.
Melissa is officially leaving us for medical school at UBC. We wish her the best of luck. Melissa was the first researcher in the lab and has been an amazing asset in getting the lab equipped and the first research projects up and running.
CIHR New investigator and CIHR open operating grant funded, a great sigh of relief by all in the lab.